Reaction Details Report a problem with these data
Target
Delta-type opioid receptor
Ligand
BDBM88486
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>92452±n/a nM
Citation
PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID]
More Info.:
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
Inhibitor
Name:
BDBM88486
Synonyms:
1-(4-chlorobenzyl)-2,4,6-triphenyl-pyridin-1-ium;perchlorate | 1-[(4-chlorophenyl)methyl]-2,4,6-triphenyl-pyridin-1-ium;perchlorate | 1-[(4-chlorophenyl)methyl]-2,4,6-triphenylpyridin-1-ium;perchlorate | MLS001240926 | SMR000841331 | cid_12402750
Type:
Small organic molecule
Emp. Form.:
C30H23ClN
Mol. Mass.:
432.963
SMILES:
Clc1ccc(C[n+]2c(cc(cc2-c2ccccc2)-c2ccccc2)-c2ccccc2)cc1