Reaction Details Report a problem with these data
Target
Delta-type opioid receptor
Ligand
BDBM48733
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>64603±n/a nM
Citation
PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID]
More Info.:
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
Inhibitor
Name:
BDBM48733
Synonyms:
1-cetyl-N,N-diethyl-pyridin-1-ium-3-carboxamide;bromide | 1-cetyl-N,N-diethyl-pyridin-1-ium-3-carboxamide;chloride | 3-Diethylcarbamoyl-1-hexadecyl-pyridinium | MLS000587364 | N,N-diethyl-1-hexadecyl-3-pyridin-1-iumcarboxamide;bromide | N,N-diethyl-1-hexadecyl-pyridin-1-ium-3-carboxamide;bromide | N,N-diethyl-1-hexadecylpyridin-1-ium-3-carboxamide;bromide | SMR000211414 | cid_12005597
Type:
Small organic molecule
Emp. Form.:
C26H47N2O
Mol. Mass.:
403.6636
SMILES:
CCCCCCCCCCCCCCCC[n+]1cccc(c1)C(=O)N(CC)CC