Target
Delta-type opioid receptor
Ligand
BDBM88497
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>64552±n/a nM
Citation
 PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM88497
Synonyms:
(E)-1-[1-ethyl-4-hydroxy-4-[(E)-2-(4-propan-2-ylphenyl)ethenyl]-3-piperidinyl]-3-(4-propan-2-ylphenyl)-2-propen-1-one;hydrochloride | (E)-1-[1-ethyl-4-hydroxy-4-[(E)-2-(4-propan-2-ylphenyl)ethenyl]piperidin-3-yl]-3-(4-propan-2-ylphenyl)prop-2-en-1-one;hydrochloride | (E)-1-[1-ethyl-4-hydroxy-4-[(E)-2-p-cumenylvinyl]-3-piperidyl]-3-p-cumenyl-prop-2-en-1-one;hydrochloride | (E)-1-[1-ethyl-4-oxidanyl-4-[(E)-2-(4-propan-2-ylphenyl)ethenyl]piperidin-3-yl]-3-(4-propan-2-ylphenyl)prop-2-en-1-one;hydrochloride | MLS002702405 | SMR001565967 | cid_5469647
Type:
Small organic molecule
Emp. Form.:
C30H39NO2
Mol. Mass.:
445.6362
SMILES:
CCN1CCC(O)(\C=C\c2ccc(cc2)C(C)C)C(C1)C(=O)C=Cc1ccc(cc1)C(C)C |w:22.23|
Structure:
Search PDB for entries with ligand similarity: