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Target
Delta-type opioid receptor
Ligand
BDBM88510
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>64561±n/a nM
Citation
 PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM88510
Synonyms:
MLS003124196 | N-[3-(4-fluorophenyl)-6-(3-pyridinyl)-8-imidazo[1,2-a]pyridinyl]acetamide | N-[3-(4-fluorophenyl)-6-(3-pyridyl)imidazo[1,2-a]pyridin-8-yl]acetamide | N-[3-(4-fluorophenyl)-6-pyridin-3-yl-imidazo[1,2-a]pyridin-8-yl]ethanamide | N-[3-(4-fluorophenyl)-6-pyridin-3-ylimidazo[1,2-a]pyridin-8-yl]acetamide | SMR001292695 | cid_46943089
Type:
Small organic molecule
Emp. Form.:
C20H15FN4O
Mol. Mass.:
346.3577
SMILES:
CC(=O)Nc1cc(cn2c(cnc12)-c1ccc(F)cc1)-c1cccnc1
Structure:
Search PDB for entries with ligand similarity: