Target
Delta-type opioid receptor
Ligand
BDBM88516
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>92496±n/a nM
Citation
 PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM88516
Synonyms:
1-[2-(2,4-dichlorophenoxy)ethyl]-N-[(4-fluorophenyl)-(3-methyl-2-pyridinyl)methyl]-N-methyl-4-piperidinecarboxamide | 1-[2-(2,4-dichlorophenoxy)ethyl]-N-[(4-fluorophenyl)-(3-methyl-2-pyridyl)methyl]-N-methyl-isonipecotamide | 1-[2-(2,4-dichlorophenoxy)ethyl]-N-[(4-fluorophenyl)-(3-methylpyridin-2-yl)methyl]-N-methylpiperidine-4-carboxamide | 1-[2-[2,4-bis(chloranyl)phenoxy]ethyl]-N-[(4-fluorophenyl)-(3-methylpyridin-2-yl)methyl]-N-methyl-piperidine-4-carboxamide | MLS003121715 | SMR001284801 | cid_46943740
Type:
Small organic molecule
Emp. Form.:
C28H30Cl2FN3O2
Mol. Mass.:
530.461
SMILES:
CN(C(c1ccc(F)cc1)c1ncccc1C)C(=O)C1CCN(CCOc2ccc(Cl)cc2Cl)CC1
Structure:
Search PDB for entries with ligand similarity: