Target
Delta-type opioid receptor
Ligand
BDBM88522
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>92494±n/a nM
Citation
 PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM88522
Synonyms:
4-[1-amino-2-(4-chlorophenyl)ethyl]-N-(4,6-dimethyl-2-pyrimidinyl)-2-thiazolamine | 4-[1-amino-2-(4-chlorophenyl)ethyl]-N-(4,6-dimethylpyrimidin-2-yl)-1,3-thiazol-2-amine | 4-[1-azanyl-2-(4-chlorophenyl)ethyl]-N-(4,6-dimethylpyrimidin-2-yl)-1,3-thiazol-2-amine | MLS003123700 | SMR001291736 | [4-[1-amino-2-(4-chlorophenyl)ethyl]thiazol-2-yl]-(4,6-dimethylpyrimidin-2-yl)amine | cid_46948249
Type:
Small organic molecule
Emp. Form.:
C17H18ClN5S
Mol. Mass.:
359.876
SMILES:
Cc1cc(C)nc(Nc2nc(cs2)C(N)Cc2ccc(Cl)cc2)n1
Structure:
Search PDB for entries with ligand similarity: