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Target
Melanocortin receptor 4
Ligand
BDBM88575
Substrate
n/a
Meas. Tech.
TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R)
IC50
>64599±n/a nM
Citation
 PubChem, PC TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88575
Synonyms:
2-[(7-chloranyl-1,2,3,4-tetrahydroacridin-9-yl)sulfanyl]-1-[4-(furan-2-ylcarbonyl)piperazin-1-yl]ethanone | 2-[(7-chloro-1,2,3,4-tetrahydroacridin-9-yl)sulfanyl]-1-[4-(furan-2-carbonyl)piperazin-1-yl]ethanone | 2-[(7-chloro-1,2,3,4-tetrahydroacridin-9-yl)thio]-1-[4-(2-furoyl)piperazino]ethanone | 2-[(7-chloro-1,2,3,4-tetrahydroacridin-9-yl)thio]-1-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]ethanone | 7-chloro-9-({2-[4-(2-furoyl)piperazin-1-yl]-2-oxoethyl}thio)-1,2,3,4-tetrahydroacridine | MLS000045516 | SMR000027273 | cid_3239595
Type:
Small organic molecule
Emp. Form.:
C24H24ClN3O3S
Mol. Mass.:
469.984
SMILES:
Clc1ccc2nc3CCCCc3c(SCC(=O)N3CCN(CC3)C(=O)c3ccco3)c2c1
Structure:
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