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Target
Melanocortin receptor 4
Ligand
BDBM54800
Substrate
n/a
Meas. Tech.
TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R)
IC50
>64583±n/a nM
Citation
 PubChem, PC TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM54800
Synonyms:
2-[1-[(E)-1-(2-furanyl)-3-(4-methoxyphenyl)-3-oxoprop-1-en-2-yl]-2-pyridinylidene]propanedinitrile | 2-[1-[(E)-1-(furan-2-yl)-3-(4-methoxyphenyl)-3-oxidanylidene-prop-1-en-2-yl]pyridin-2-ylidene]propanedinitrile | 2-[1-[(E)-1-(furan-2-yl)-3-(4-methoxyphenyl)-3-oxoprop-1-en-2-yl]pyridin-2-ylidene]propanedinitrile | 2-[1-[(E)-2-(2-furyl)-1-p-anisoyl-vinyl]-2-pyridylidene]malononitrile | 2-{1-[2-Furan-2-yl-1-(4-methoxy-benzoyl)-vinyl]-1H-pyridin-2-ylidene}-malononitrile | MLS000555673 | SMR000176548 | cid_5761997
Type:
Small organic molecule
Emp. Form.:
C22H15N3O3
Mol. Mass.:
369.3728
SMILES:
COc1ccc(cc1)C(=O)C(=C/c1ccco1)\N1C=CC=CC1=C(C#N)C#N |c:20,22,(15.5,1.39,;14.16,2.16,;12.83,1.39,;11.49,2.16,;10.16,1.39,;10.16,-.15,;11.49,-.92,;12.83,-.15,;8.83,-.92,;8.83,-2.46,;7.49,-.15,;6.16,-.92,;6.16,-2.46,;4.91,-3.36,;5.39,-4.83,;6.93,-4.83,;7.41,-3.36,;7.49,1.39,;8.83,2.16,;8.83,3.7,;7.49,4.47,;6.16,3.7,;6.16,2.16,;4.62,2.16,;3.85,3.5,;3.08,4.83,;3.85,.83,;3.08,-.51,)|
Structure:
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