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Target
Melanocortin receptor 4
Ligand
BDBM88605
Substrate
n/a
Meas. Tech.
TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R)
IC50
>64592±n/a nM
Citation
 PubChem, PC TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88605
Synonyms:
MLS000335805 | N-[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]-2-(1,3,4-thiadiazol-2-ylsulfanyl)propanamide | N-[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]-2-(1,3,4-thiadiazol-2-ylthio)propanamide | N-[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]-2-(1,3,4-thiadiazol-2-ylthio)propionamide | SMR000253559 | cid_4881126
Type:
Small organic molecule
Emp. Form.:
C19H16N4OS3
Mol. Mass.:
412.552
SMILES:
CC(Sc1nncs1)C(=O)Nc1ccc(cc1)-c1nc2ccc(C)cc2s1
Structure:
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