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Target26S Proteasome regulatory subunit Rpn11 (Rpn11)
LigandBDBM88918
Substrate/Competitorn/a
Meas. Tech.Dose response confirmation of uHTS RPN11 inhibitor hits in a Fluorescence Polarization assay
IC50 1820±186 nM
Citation PubChem, PC Dose response confirmation of uHTS RPN11 inhibitor hits in a Fluorescence Polarization assay PubChem Bioassay(2012)[AID]
More Info.:Get all data from this article,  Assay Method
 
26S Proteasome regulatory subunit Rpn11 (Rpn11)
Name:26S Proteasome regulatory subunit Rpn11 (Rpn11)
Synonyms:PSMD14 protein
Type:Protein
Mol. Mass.:34576.68
Organism:Homo sapiens (Human)
Description:O00487
Residue:310
Sequence:
MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGE
FVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGC
WLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSN
LGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKH
NESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCL
AAMLDTVVFK
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BDBM88918
NameBDBM88918
Synonyms:MLS001006760 | N-[(E)-1-(1-benzofuran-2-yl)ethylideneamino]-4-nitro-aniline | N-[(E)-1-(1-benzofuran-2-yl)ethylideneamino]-4-nitroaniline | N-[(E)-1-(2-benzofuranyl)ethylideneamino]-4-nitroaniline | SMR000349686 | [(E)-1-(benzofuran-2-yl)ethylideneamino]-(4-nitrophenyl)amine | cid_9658313
TypeSmall organic molecule
Emp. Form.C16H13N3O3
Mol. Mass.295.2927
SMILESC[C-](\N=[NH+]\c1ccc(cc1)[N+]([O-])=O)c1cc2ccccc2o1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a