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Target
Tyrosine-protein phosphatase non-receptor type 5
Ligand
BDBM82624
Substrate
n/a
Meas. Tech.
Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay
IC50
58800±n/a nM
Citation
 PubChem, PC Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay PubChem Bioassay (2012)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 5
Synonyms:
PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
63510.68
Organism:
Homo sapiens (Human)
Description:
gi_90652859
Residue:
565
Sequence:
MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPPPPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLVSSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPEDRRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQSPE
  
Inhibitor
Name:
BDBM82624
Synonyms:
5-(4-ethyl-5-keto-3-methyl-3-pyrazolin-1-yl)-2-phenoxy-besylic acid | 5-(4-ethyl-5-methyl-3-oxidanylidene-1H-pyrazol-2-yl)-2-phenoxy-benzenesulfonic acid | 5-(4-ethyl-5-methyl-3-oxo-1H-pyrazol-2-yl)-2-phenoxybenzenesulfonic acid | MLS000105676 | SMR000102654 | cid_2193708
Type:
Small organic molecule
Emp. Form.:
C18H18N2O5S
Mol. Mass.:
374.411
SMILES:
CCc1c(C)[nH]n(-c2ccc(Oc3ccccc3)c(c2)S(O)(=O)=O)c1=O
Structure:
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