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Target
Tyrosine-protein phosphatase non-receptor type 5
Ligand
BDBM88785
Substrate
n/a
Meas. Tech.
Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay
IC50
>80000±n/a nM
Citation
 PubChem, PC Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay PubChem Bioassay (2012)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 5
Synonyms:
PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
63510.68
Organism:
Homo sapiens (Human)
Description:
gi_90652859
Residue:
565
Sequence:
MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPPPPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLVSSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPEDRRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQSPE
  
Inhibitor
Name:
BDBM88785
Synonyms:
MLS001202227 | N-(3-fluoranyl-4-methyl-phenyl)-3-(2-sulfanylidene-1,3-benzoxazol-3-yl)propanamide | N-(3-fluoro-4-methyl-phenyl)-3-(2-thioxo-1,3-benzoxazol-3-yl)propionamide | N-(3-fluoro-4-methylphenyl)-3-(2-sulfanylidene-1,3-benzoxazol-3-yl)propanamide | N-(3-fluoro-4-methylphenyl)-3-(2-thioxo-1,3-benzoxazol-3(2H)-yl)propanamide | SMR000564947 | cid_5064419
Type:
Small organic molecule
Emp. Form.:
C17H15FN2O2S
Mol. Mass.:
330.377
SMILES:
Cc1ccc(NC(=O)CCn2c3ccccc3oc2=S)cc1F
Structure:
Search PDB for entries with ligand similarity: