Reaction Details Report a problem with these data
Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM89108
Substrate
n/a
Meas. Tech.
SAR analysis of small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen.
IC50
>99000±n/a nM
Citation
 PubChem, PC SAR analysis of small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen. PubChem Bioassay (2012)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM89108
Synonyms:
MLS-0463375.0001 | N-(1H-pyrazol-5-yl)-3-(3-pyridinylmethoxy)benzamide | N-(1H-pyrazol-5-yl)-3-(3-pyridylmethoxy)benzamide | N-(1H-pyrazol-5-yl)-3-(pyridin-3-ylmethoxy)benzamide | cid_51097483
Type:
Small organic molecule
Emp. Form.:
C16H14N4O2
Mol. Mass.:
294.308
SMILES:
O=C(Nc1ccn[nH]1)c1cccc(OCc2cccnc2)c1
Structure:
Search PDB for entries with ligand similarity: