Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM89046
Substrate
n/a
Meas. Tech.
SAR analysis of small molecule inhibitors of tim23-1: a luminescent TIM10 yeast counterscreen.
IC50
83080±n/a nM
Citation
 PubChem, PC SAR analysis of small molecule inhibitors of tim23-1: a luminescent TIM10 yeast counterscreen. PubChem Bioassay (2012)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM89046
Synonyms:
2-naphthalenecarboxylic acid [(Z)-[amino-(4-iodophenyl)methylidene]amino] ester | MLS-0454716.0001 | [(Z)-[amino-(4-iodophenyl)methylidene]amino] naphthalene-2-carboxylate | [(Z)-[azanyl-(4-iodophenyl)methylidene]amino] naphthalene-2-carboxylate | cid_9567404 | naphthalene-2-carboxylic acid [(Z)-[amino-(4-iodophenyl)methylene]amino] ester
Type:
Small organic molecule
Emp. Form.:
C18H13IN2O2
Mol. Mass.:
416.2125
SMILES:
NC(=NOC(=O)c1ccc2ccccc2c1)c1ccc(I)cc1 |w:2.2|
Structure:
Search PDB for entries with ligand similarity: