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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM83274
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex
EC50
870±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM83274
Synonyms:
1-[(7-nitro-9H-fluoren-2-yl)-(2-oxidanylpropyl)amino]propan-2-ol | 1-[2-hydroxypropyl-(7-nitro-9H-fluoren-2-yl)amino]-2-propanol | 1-[2-hydroxypropyl-(7-nitro-9H-fluoren-2-yl)amino]propan-2-ol | MLS002667450 | SMR001557216 | cid_242563
Type:
Small organic molecule
Emp. Form.:
C19H22N2O4
Mol. Mass.:
342.389
SMILES:
CC(O)CN(CC(C)O)c1ccc-2c(Cc3cc(ccc-23)[N+]([O-])=O)c1
Structure:
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