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Target
ATP-binding cassette sub-family B member 6
Ligand
BDBM91489
Substrate
n/a
Meas. Tech.
Dose Response of Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for Cherry Pick01
EC50
4138±n/a nM
Citation
 PubChem, PC Dose Response of Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for Cherry Pick01 PubChem Bioassay (2012)[AID] 
Target
Name:
ATP-binding cassette sub-family B member 6
Synonyms:
ABCB6 | ABCB6_HUMAN | ATP-binding cassette sub-family B member 6, mitochondrial | MTABC3 | PRP | UMAT
Type:
Enzyme Catalytic Domain
Mol. Mass.:
93896.51
Organism:
Homo sapiens (Human)
Description:
gi_9955963
Residue:
842
Sequence:
MVTVGNYCEAEGPVGPAWMQDGLSPCFFFTLVPSTRMALGTLALVLALPCRRRERPAGADSLSWGAGPRISPYVLQLLLATLQAALPLAGLAGRVGTARGAPLPSYLLLASVLESLAGACGLWLLVVERSQARQRLAMGIWIKFRHSPGLLLLWTVAFAAENLALVSWNSPQWWWARADLGQQVQFSLWVLRYVVSGGLFVLGLWAPGLRPQSYTLQVHEEDQDVERSQVRSAAQQSTWRDFGRKLRLLSGYLWPRGSPALQLVVLICLGLMGLERALNVLVPIFYRNIVNLLTEKAPWNSLAWTVTSYVFLKFLQGGGTGSTGFVSNLRTFLWIRVQQFTSRRVELLIFSHLHELSLRWHLGRRTGEVLRIADRGTSSVTGLLSYLVFNVIPTLADIIIGIIYFSMFFNAWFGLIVFLCMSLYLTLTIVVTEWRTKFRRAMNTQENATRARAVDSLLNFETVKYYNAESYEVERYREAIIKYQGLEWKSSASLVLLNQTQNLVIGLGLLAGSLLCAYFVTEQKLQVGDYVLFGTYIIQLYMPLNWFGTYYRMIQTNFIDMENMFDLLKEETEVKDLPGAGPLRFQKGRIEFENVHFSYADGRETLQDVSFTVMPGQTLALVGPSGAGKSTILRLLFRFYDISSGCIRIDGQDISQVTQASLRSHIGVVPQDTVLFNDTIADNIRYGRVTAGNDEVEAAAQAAGIHDAIMAFPEGYRTQVGERGLKLSGGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAKVCANRTTIVVAHRLSTVVNADQILVIKDGCIVERGRHEALLSRGGVYADMWQLQQGQEETSEDTKPQTMER
  
Inhibitor
Name:
BDBM91489
Synonyms:
MLS002701786 | SMR001565380 | [2-keto-3-[(trimethylammonio)methyl]cyclohexyl]methyl-trimethyl-ammonium;iodide | cid_360569 | trimethyl-[[2-oxidanylidene-3-[(trimethylazaniumyl)methyl]cyclohexyl]methyl]azanium;iodide | trimethyl-[[2-oxo-3-[(trimethylammonio)methyl]cyclohexyl]methyl]ammonium;iodide | trimethyl-[[2-oxo-3-[(trimethylazaniumyl)methyl]cyclohexyl]methyl]azanium;iodide
Type:
Small organic molecule
Emp. Form.:
C14H30N2O
Mol. Mass.:
242.3997
SMILES:
C[N+](C)(C)CC1CCCC(C[N+](C)(C)C)C1=O
Structure:
Search PDB for entries with ligand similarity: