Reaction Details Report a problem with these data
Target
Mitochondrial peptide methionine sulfoxide reductase
Ligand
BDBM42260
Substrate
n/a
Meas. Tech.
Absorbance-based biochemical high throughput dose response assay for activators of Methionine sulfoxide reductase A (MsrA)
EC50
57522±n/a nM
Citation
 PubChem, PC Absorbance-based biochemical high throughput dose response assay for activators of Methionine sulfoxide reductase A (MsrA) PubChem Bioassay (2012)[AID] 
Target
Name:
Mitochondrial peptide methionine sulfoxide reductase
Synonyms:
MSRA | MSRA protein | MSRA_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25822.90
Organism:
Bos taurus
Description:
gi_73586699
Residue:
233
Sequence:
MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK
  
Inhibitor
Name:
BDBM42260
Synonyms:
(2-anilino-2-oxoethyl) 5-nitrothiophene-2-carboxylate | (2-oxidanylidene-2-phenylazanyl-ethyl) 5-nitrothiophene-2-carboxylate | 5-nitro-2-thiophenecarboxylic acid (2-anilino-2-oxoethyl) ester | 5-nitrothiophene-2-carboxylic acid (2-anilino-2-keto-ethyl) ester | MLS000392367 | SMR000261354 | cid_2401195
Type:
Small organic molecule
Emp. Form.:
C13H10N2O5S
Mol. Mass.:
306.294
SMILES:
[O-][N+](=O)c1ccc(s1)C(=O)OCC(=O)Nc1ccccc1
Structure:
Search PDB for entries with ligand similarity: