Reaction Details Report a problem with these data
Target
Mitochondrial peptide methionine sulfoxide reductase
Ligand
BDBM91498
Substrate
n/a
Meas. Tech.
Absorbance-based biochemical high throughput dose response assay for activators of Methionine sulfoxide reductase A (MsrA)
EC50
>103909±n/a nM
Citation
 PubChem, PC Absorbance-based biochemical high throughput dose response assay for activators of Methionine sulfoxide reductase A (MsrA) PubChem Bioassay (2012)[AID] 
Target
Name:
Mitochondrial peptide methionine sulfoxide reductase
Synonyms:
MSRA | MSRA protein | MSRA_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25822.90
Organism:
Bos taurus
Description:
gi_73586699
Residue:
233
Sequence:
MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK
  
Inhibitor
Name:
BDBM91498
Synonyms:
(2S)-2-benzamido-3-methyl-butyric acid (4-keto-5-phenyl-3H-thieno[2,3-d]pyrimidin-2-yl)methyl ester | (2S)-2-benzamido-3-methylbutanoic acid (4-oxo-5-phenyl-3H-thieno[2,3-d]pyrimidin-2-yl)methyl ester | (4-oxidanylidene-5-phenyl-3H-thieno[2,3-d]pyrimidin-2-yl)methyl (2S)-2-benzamido-3-methyl-butanoate | (4-oxo-5-phenyl-3H-thieno[2,3-d]pyrimidin-2-yl)methyl (2S)-2-benzamido-3-methylbutanoate | MLS000339514 | SMR000244129 | cid_2450183
Type:
Small organic molecule
Emp. Form.:
C25H23N3O4S
Mol. Mass.:
461.533
SMILES:
CC(C)[C@H](NC(=O)c1ccccc1)C(=O)OCc1nc2scc(-c3ccccc3)c2c(=O)[nH]1
Structure:
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