Reaction Details Report a problem with these data
Target
Chymotrypsin-C
Ligand
BDBM113065
Substrate
n/a
Meas. Tech.
Chymotrypsin Assay
pH
7.2±n/a
Temperature
310.15±n/a K
Ki
>10000±n/a nM
Comments
extracted
Citation
 Wagberg, F; Leonardsson, G Benzoxazinone derivatives for treatment of skin diseases US Patent  US9695194 Publication Date 7/4/2017 
Target
Name:
Chymotrypsin-C
Synonyms:
CLCR | CTRC | CTRC_HUMAN | Caldecrin | Chymotrypsin | Chymotrypsin C | Chymotrypsin-C
Type:
Enzyme
Mol. Mass.:
29487.98
Organism:
Homo sapiens (Human)
Description:
Q99895
Residue:
268
Sequence:
MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL
  
Inhibitor
Name:
BDBM113065
Synonyms:
US9695194, 2
Type:
Small organic molecule
Emp. Form.:
C17H14ClNO4
Mol. Mass.:
331.75
SMILES:
CCOc1cc2c(cc1OC)nc(oc2=O)-c1ccccc1Cl
Structure:
Search PDB for entries with ligand similarity: