Reaction Details Report a problem with these data
Target
Serine protease 1
Ligand
BDBM113301
Substrate
n/a
Meas. Tech.
Trypsin Assay
pH
7.2±n/a
Temperature
310.15±n/a K
Ki
>10000±n/a nM
Comments
extracted
Citation
 Wagberg, F; Leonardsson, G Benzoxazinone derivatives for treatment of skin diseases US Patent  US9695194 Publication Date 7/4/2017 
Target
Name:
Serine protease 1
Synonyms:
Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1
Type:
Enzyme
Mol. Mass.:
26557.80
Organism:
Homo sapiens (Human)
Description:
P07477
Residue:
247
Sequence:
MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS
  
Inhibitor
Name:
BDBM113301
Synonyms:
US9695194, 17
Type:
Small organic molecule
Emp. Form.:
C18H17NO6
Mol. Mass.:
343.3307
SMILES:
COc1ccc(c(OC)c1)-c1nc2cc(OC)c(OC)cc2c(=O)o1
Structure:
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