Reaction Details Report a problem with these data
Target
Tyrosine-protein phosphatase non-receptor type 5
Ligand
BDBM81100
Substrate
n/a
Meas. Tech.
Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay.
IC50
21300±n/a nM
Citation
 PubChem, PC Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay. PubChem Bioassay (2012)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 5
Synonyms:
PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
63510.68
Organism:
Homo sapiens (Human)
Description:
gi_90652859
Residue:
565
Sequence:
MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPPPPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLVSSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPEDRRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQSPE
  
Inhibitor
Name:
BDBM81100
Synonyms:
1-[5-[(4-chlorophenyl)sulfamoyl]-2-(4-morpholinyl)phenyl]-3-[2-(4-morpholinyl)ethyl]thiourea | 1-[5-[(4-chlorophenyl)sulfamoyl]-2-morpholin-4-yl-phenyl]-3-(2-morpholin-4-ylethyl)thiourea | 1-[5-[(4-chlorophenyl)sulfamoyl]-2-morpholin-4-ylphenyl]-3-(2-morpholin-4-ylethyl)thiourea | 1-[5-[(4-chlorophenyl)sulfamoyl]-2-morpholino-phenyl]-3-(2-morpholinoethyl)thiourea | MLS000774726 | SMR000372487 | cid_3578672
Type:
Small organic molecule
Emp. Form.:
C23H30ClN5O4S2
Mol. Mass.:
540.098
SMILES:
Clc1ccc(NS(=O)(=O)c2ccc(N3CCOCC3)c(NC(=S)NCCN3CCOCC3)c2)cc1
Structure:
Search PDB for entries with ligand similarity: