Reaction Details Report a problem with these data
Target
Prostaglandin G/H synthase 1 [582-599]
Ligand
BDBM91679
Substrate
n/a
Meas. Tech.
Enzyme Inhibition Assay
IC50
7.641e+4± 2.2e+2 nM
Citation
 Bekhit, AA; Ashour, HM; Bekhit, Ael-D; Abdel-Rahman, HM; Bekhit, SA Synthesis of some pyrazolyl benzenesulfonamide derivatives as dual anti-inflammatory antimicrobial agents. J Enzyme Inhib Med Chem 24:296-309 (2009) [PubMed]  Article 
Target
Name:
Prostaglandin G/H synthase 1 [582-599]
Synonyms:
COX-1 | COX1 | Cyclooxygenase | Cyclooxygenase-1 | Cyclooxygenase-1 (COX-1) | PGH synthase 1 | PGH1_HUMAN | PGHS-1 | PHS 1 | PTGS1 | Prostaglandin G/H synthase 1 | Prostaglandin H2 synthase 1 | Prostaglandin-endoperoxide synthase 1
Type:
Protein
Mol. Mass.:
1879.89
Organism:
Homo sapiens (Human)
Description:
Q6LCE7
Residue:
18
Sequence:
PDASQDDGPAVERPSTEL
  
Inhibitor
Name:
BDBM91679
Synonyms:
Pyrazolyl benzenesulfonamide derivative, 7b
Type:
Small organic molecule
Emp. Form.:
C17H16N4O3S
Mol. Mass.:
356.399
SMILES:
Cc1ccc(cc1)-c1nn(cc1C(N)=O)-c1ccc(cc1)S(N)(=O)=O
Structure:
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