Reaction Details Report a problem with these data
Target
Cyclin-dependent kinase 2
Ligand
BDBM7163
Substrate
n/a
Meas. Tech.
OctetRed
pH
7.5±n/a
Temperature
298.15±n/a K
Kd
910±227 nM
Citation
 CSARdock, CD CDK2 in CSAR_FULL_RELEASE_3JULY2012 CSAR 1:0 (2012)  
Target
Name:
Cyclin-dependent kinase 2
Synonyms:
CDK2 | CDK2-Kinase | CDK2_HUMAN | CDKN2 | Cell division protein kinase 2 | Cyclin-dependent kinase 2 (CDK2) | Protein cereblon/Cyclin-dependent kinase 2 | p33 protein kinase
Type:
Enzyme Subunit
Mol. Mass.:
33938.17
Organism:
Homo sapiens (Human)
Description:
P24941
Residue:
298
Sequence:
MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
  
Inhibitor
Name:
BDBM7163
Synonyms:
3-Phenylacetamidoaminopyrazole deriv. 40 | CS10 | N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-(4-thien-2-ylphenyl)acetamide | N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-[4-(thiophen-2-yl)phenyl]acetamide
Type:
Small organic molecule
Emp. Form.:
C18H17N3OS
Mol. Mass.:
323.412
SMILES:
O=C(Cc1ccc(cc1)-c1cccs1)Nc1cc(n[nH]1)C1CC1
Structure:
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