Reaction Details Report a problem with these data
Target
Urokinase-type plasminogen activator
Ligand
BDBM92305
Substrate
n/a
Meas. Tech.
Abbott uPA__Urokinase Human - Ki(uM)
pH
7.4±n/a
Temperature
298.15±n/a K
Ki
290±n/a nM
Citation
 CSARdock, CD UROKINASE in CSAR_FULL_RELEASE_3JULY2012 CSAR 1:0 (2012)  
Target
Name:
Urokinase-type plasminogen activator
Synonyms:
PLAU | U-plasminogen activator | UROK_HUMAN | Urokinase | Urokinase-type plasminogen activator (uPA) | Urokinase-type plasminogen activator/surface receptor
Type:
Enzyme
Mol. Mass.:
48528.62
Organism:
Homo sapiens (Human)
Description:
P00749
Residue:
431
Sequence:
MRALLARLLLCVLVVSDSKGSNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQHCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRRRPWCYVQVGLKPLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTKEENGLAL
  
Inhibitor
Name:
BDBM92305
Synonyms:
uPa_29
Type:
n/a
Emp. Form.:
C27H22N4O
Mol. Mass.:
418.4898
SMILES:
NC(=N)c1ccc2cc(ccc2c1)C(=O)Nc1ccc2CCN=C(c3ccccc3)c2c1 |t:24|
Structure:
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