Reaction Details Report a problem with these data
Target
PhoP
Ligand
BDBM50326557
Substrate
n/a
Meas. Tech.
Inhibition Assay
IC50
1.2e+4±n/a nM
Citation
 Tang, YT; Gao, R; Havranek, JJ; Groisman, EA; Stock, AM; Marshall, GR Inhibition of bacterial virulence: drug-like molecules targeting the Salmonella enterica PhoP response regulator. Chem Biol Drug Des 79:1007-17 (2012) [PubMed]  Article 
Target
Name:
PhoP
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
24274.92
Organism:
Salmonella enterica
Description:
A6XC03
Residue:
213
Sequence:
MRVLVVEDNALLRHHLKVQLQDSGHQVDAAEDAREADYYLNEHLPDIAIVDLGLPDEDGLSLIRRWRSSDVSLPVLVLTAREGWQDKVEVLSSGADDYVTKPFHIEEVMARMQALMRRNSGLASQVINIPPFQVDLSRRELSVNEEVIKLTAFEYTIMETLIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAQYPHDVITTV
  
Inhibitor
Name:
BDBM50326557
Synonyms:
(E)-5-((2-hydroxynaphthalen-1-yl)diazenyl)naphthalene-2-sulfonic acid | CHEMBL1253920 | NSC45576, 2
Type:
Small organic molecule
Emp. Form.:
C20H14N2O4S
Mol. Mass.:
378.401
SMILES:
Oc1ccc2ccccc2c1N=Nc1cccc2cc(ccc12)S(O)(=O)=O |w:12.14|
Structure:
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