Reaction Details Report a problem with these data
Target
PhoP
Ligand
BDBM92341
Substrate
n/a
Meas. Tech.
Inhibition Assay
IC50
14000000±0.0 nM
Citation
 Tang, YT; Gao, R; Havranek, JJ; Groisman, EA; Stock, AM; Marshall, GR Inhibition of bacterial virulence: drug-like molecules targeting the Salmonella enterica PhoP response regulator. Chem Biol Drug Des 79:1007-17 (2012) [PubMed]  Article 
Target
Name:
PhoP
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
24274.92
Organism:
Salmonella enterica
Description:
A6XC03
Residue:
213
Sequence:
MRVLVVEDNALLRHHLKVQLQDSGHQVDAAEDAREADYYLNEHLPDIAIVDLGLPDEDGLSLIRRWRSSDVSLPVLVLTAREGWQDKVEVLSSGADDYVTKPFHIEEVMARMQALMRRNSGLASQVINIPPFQVDLSRRELSVNEEVIKLTAFEYTIMETLIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAQYPHDVITTV
  
Inhibitor
Name:
BDBM92341
Synonyms:
NSC35489, 4
Type:
Small organic molecule
Emp. Form.:
C25H18NO
Mol. Mass.:
348.416
SMILES:
O=C(C[n+]1ccc2ccccc2c1)c1ccc2ccc3ccccc3c2c1
Structure:
Search PDB for entries with ligand similarity: