Reaction Details Report a problem with these data
Target
Alpha-(1,3)-fucosyltransferase 7
Ligand
BDBM92458
Substrate
n/a
Meas. Tech.
SPA Assay
pH
7.3±0
Temperature
295.15±0 K
IC50
>200000±0.0 nM
Citation
 Niu, X; Fan, X; Sun, J; Ting, P; Narula, S; Lundell, D Inhibition of fucosyltransferase VII by gallic acid and its derivatives. Arch Biochem Biophys 425:51-7 (2004) [PubMed]  Article 
Target
Name:
Alpha-(1,3)-fucosyltransferase 7
Synonyms:
Alpha-(1,3)-fucosyltransferase VII | FUT7 | FUT7_HUMAN | Fucosyltransferase VII | Fuct VII
Type:
n/a
Mol. Mass.:
39259.56
Organism:
Homo sapiens (Human)
Description:
Q11130
Residue:
342
Sequence:
MNNAGHGPTRRLRGLGVLAGVALLAALWLLWLLGSAPRGTPAPQPTITILVWHWPFTDQPPELPSDTCTRYGIARCHLSANRSLLASADAVVFHHRELQTRRSHLPLAQRPRGQPWVWASMESPSHTHGLSHLRGIFNWVLSYRRDSDIFVPYGRLEPHWGPSPPLPAKSRVAAWVVSNFQERQLRARLYRQLAPHLRVDVFGRANGRPLCASCLVPTVAQYRFYLSFENSQHRDYITEKFWRNALVAGTVPVVLGPPRATYEAFVPADAFVHVDDFGSARELAAFLTGMNESRYQRFFAWRDRLRVRLFTDWRERFCAICDRYPHLPRSQVYEDLEGWFQA
  
Inhibitor
Name:
BDBM92458
Synonyms:
3,4,5-trimethoxybenzoic acid
Type:
Small molecule
Emp. Form.:
C10H12O5
Mol. Mass.:
212.1993
SMILES:
COc1cc(cc(OC)c1OC)C(O)=O
Structure:
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