Reaction Details Report a problem with these data
Target
Cytochrome P450 130
Ligand
BDBM92569
Substrate
n/a
Meas. Tech.
Binding Assay
Kd
1.08e+3± 2e+1 nM
Citation
 Podust, LM; Ouellet, H; von Kries, JP; de Montellano, PR Interaction of Mycobacterium tuberculosis CYP130 with heterocyclic arylamines. J Biol Chem 284:25211-9 (2009) [PubMed]  Article 
Target
Name:
Cytochrome P450 130
Synonyms:
CP130_MYCTO | Putative cytochrome P450 130 | cyp130
Type:
Enzyme
Mol. Mass.:
44574.98
Organism:
Mycobacterium tuberculosis
Description:
P9WPN4
Residue:
405
Sequence:
MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS
  
Inhibitor
Name:
BDBM92569
Synonyms:
Arylamine compound 2
Type:
Small organic molecule
Emp. Form.:
C20H15N3O2S
Mol. Mass.:
361.417
SMILES:
Nc1ccc(Sc2ccc(cc2)N2C(=O)c3ccc(N)cc3C2=O)cc1
Structure:
Search PDB for entries with ligand similarity: