Reaction Details Report a problem with these data
Target
Cytochrome P450 2E1
Ligand
BDBM92671
Substrate
n/a
Meas. Tech.
Spectral Binding Assay
Kd
1.2e+4±n/a nM
Citation
 Ménard, A; Fabra, C; Huang, Y; Auclair, K Type II Ligands as Chemical Auxiliaries To Favor Enzymatic Transformations by P450 2E1. Chembiochem 13:2527-36 (2012) [PubMed]  Article 
Target
Name:
Cytochrome P450 2E1
Synonyms:
CP2E1_HUMAN | CYP2E | CYP2E1 | Cytochrome P450 2E1 (CYP2E1)
Type:
Enzyme
Mol. Mass.:
56860.34
Organism:
Homo sapiens (Human)
Description:
P05181
Residue:
493
Sequence:
MSALGVTVALLVWAAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMYLFNENFHLLSTPWLQLYNNFPSFLHYLPGSHRKVIKNVAEVKEYVSERVKEHHQSLDPNCPRDLTDCLLVEMEKEKHSAERLYTMDGITVTVADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKDIDLSPIHIGFGCIPPRYKLCVIPRS
  
Inhibitor
Name:
BDBM92671
Synonyms:
Auxiliary substrate, 18a
Type:
Organic molecule
Emp. Form.:
C10H11NO2
Mol. Mass.:
177.1998
SMILES:
C=CCCOC(=O)c1cccnc1
Structure:
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