Reaction Details Report a problem with these data
Target
Pyrazinamidase/nicotinamidase, PncA protein
Ligand
BDBM92855
Substrate
n/a
Meas. Tech.
GDH-Coupled Nicotinamidase Assay
Ki
153000±0 nM
Citation
 French, JB; Cen, Y; Vrablik, TL; Xu, P; Allen, E; Hanna-Rose, W; Sauve, AA Characterization of nicotinamidases: steady state kinetic parameters, classwide inhibition by nicotinaldehydes, and catalytic mechanism. Biochemistry 49:10421-39 (2010) [PubMed]  Article 
Target
Name:
Pyrazinamidase/nicotinamidase, PncA protein
Synonyms:
Nicotinamidase (BbNic) | Pyrazinamidase/nicotinamidase
Type:
Enzyme
Mol. Mass.:
19332.49
Organism:
Borrelia burgdorferi
Description:
O50718
Residue:
167
Sequence:
MINQLQNYFKNIIATKDWHCKNHVSFSNNKNGGIWPEHCVKNTWGSEFPNDLNTKRIKKVFFKGTDQYYDSYSGFYDDCIKKKQTGLQLYLKNNSINTLFITGLALDFCVKETILDAINLGFRVYLITDATRSITSTPELIIQELKKLNVLTCFSKDIFDSQSKLNI
  
Inhibitor
Name:
BDBM92855
Synonyms:
Nicotinamidase Inhibitor, 22
Type:
Small molecule
Emp. Form.:
C7H7NO2
Mol. Mass.:
137.136
SMILES:
COc1ccncc1C=O
Structure:
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