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Target
DNA repair and recombination protein RadA
Ligand
BDBM32212
Substrate
n/a
Meas. Tech.
Thermal Denaturation Assay
Kd
2100000±0.0 nM
Citation
 Scott, DE; Ehebauer, MT; Pukala, T; Marsh, M; Blundell, TL; Venkitaraman, AR; Abell, C; Hyvönen, M Using a fragment-based approach to target protein-protein interactions. Chembiochem 14:332-42 (2013) [PubMed]  Article 
Target
Name:
DNA repair and recombination protein RadA
Synonyms:
DNA repair and recombination protein (RadA) | RADA_PYRFU | radA
Type:
Protein
Mol. Mass.:
38398.93
Organism:
Pyrococcus furiosus
Description:
O74036
Residue:
349
Sequence:
MAGEEVKEIDEFEELGFEPATEETPKKKKKEKIIRSIEDLPGVGPATAEKLREAGYDTLEAIAVASPIELKEVAGISEGTALKIIQAARKAANLGTFMRADEYLKKRATIGRISTGSKSLDKLLGGGIETQAITEVFGEFGSGKTQLAHTLAVMVQLPPEEGGLNGSVIWIDTENTFRPERIREIAQNRGLDPDEVLKHIYVARAFNSNHQMLLVQQAEDKIKELLNTDRPVKLLIVDSLTSHFRSEYIGRGALAERQQKLAKHLADLHRLANLYDIAVFVTNQVQARPDAFFGDPTRPIGGHILAHSATLRVYLRKGKGGKRIARLIDAPHLPEGEAVFSITEKGIED
  
Inhibitor
Name:
BDBM32212
Synonyms:
1H-indol-5-ol | cid_16054
Type:
Small organic molecule
Emp. Form.:
C8H7NO
Mol. Mass.:
133.1473
SMILES:
Oc1ccc2[nH]ccc2c1
Structure:
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