Reaction Details Report a problem with these data
Target
DNA repair and recombination protein RadA
Ligand
BDBM24627
Substrate
n/a
Meas. Tech.
Thermal Denaturation Assay
Kd
1000000±0.0 nM
Citation
 Scott, DE; Ehebauer, MT; Pukala, T; Marsh, M; Blundell, TL; Venkitaraman, AR; Abell, C; Hyvönen, M Using a fragment-based approach to target protein-protein interactions. Chembiochem 14:332-42 (2013) [PubMed]  Article 
Target
Name:
DNA repair and recombination protein RadA
Synonyms:
DNA repair and recombination protein (RadA) | RADA_PYRFU | radA
Type:
Protein
Mol. Mass.:
38398.93
Organism:
Pyrococcus furiosus
Description:
O74036
Residue:
349
Sequence:
MAGEEVKEIDEFEELGFEPATEETPKKKKKEKIIRSIEDLPGVGPATAEKLREAGYDTLEAIAVASPIELKEVAGISEGTALKIIQAARKAANLGTFMRADEYLKKRATIGRISTGSKSLDKLLGGGIETQAITEVFGEFGSGKTQLAHTLAVMVQLPPEEGGLNGSVIWIDTENTFRPERIREIAQNRGLDPDEVLKHIYVARAFNSNHQMLLVQQAEDKIKELLNTDRPVKLLIVDSLTSHFRSEYIGRGALAERQQKLAKHLADLHRLANLYDIAVFVTNQVQARPDAFFGDPTRPIGGHILAHSATLRVYLRKGKGGKRIARLIDAPHLPEGEAVFSITEKGIED
  
Inhibitor
Name:
BDBM24627
Synonyms:
1H-indazole | Indazole, 5 | Indazole, 6
Type:
Small organic molecule
Emp. Form.:
C7H6N2
Mol. Mass.:
118.1359
SMILES:
c1n[nH]c2ccccc12
Structure:
Search PDB for entries with ligand similarity: