Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM93475
Substrate
n/a
IC50
12330±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and receptor-interacting serine-threonine kinase 2 (RIPK2) PubChem Bioassay (2012)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM93475
Synonyms:
2-benzyl-N-[2-methyl-4-(4-methylpiperazin-1-yl)phenyl]-3,4-dihydro-1H-benzo[b][1,6]naphthyridine-10-carboxamide | 2-benzyl-N-[2-methyl-4-(4-methylpiperazino)phenyl]-3,4-dihydro-1H-benzo[b][1,6]naphthyridine-10-carboxamide | MLS001007077 | N-[2-methyl-4-(4-methyl-1-piperazinyl)phenyl]-2-(phenylmethyl)-3,4-dihydro-1H-benzo[b][1,6]naphthyridine-10-carboxamide | N-[2-methyl-4-(4-methylpiperazin-1-yl)phenyl]-2-(phenylmethyl)-3,4-dihydro-1H-benzo[b][1,6]naphthyridine-10-carboxamide | SMR000384510 | cid_2557808
Type:
Small organic molecule
Emp. Form.:
C32H35N5O
Mol. Mass.:
505.6532
SMILES:
CN1CCN(CC1)c1ccc(NC(=O)c2c3CN(Cc4ccccc4)CCc3nc3ccccc23)c(C)c1
Structure:
Search PDB for entries with ligand similarity: