Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM61926
Substrate
n/a
IC50
19343±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and receptor-interacting serine-threonine kinase 2 (RIPK2) PubChem Bioassay (2012)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM61926
Synonyms:
KSC-4-254 | KUC104123N | N-(4-fluorophenyl)-2-(3-keto-1,2-benzothiazol-2-yl)acetamide | N-(4-fluorophenyl)-2-(3-oxidanylidene-1,2-benzothiazol-2-yl)ethanamide | N-(4-fluorophenyl)-2-(3-oxo-1,2-benzothiazol-2-yl)acetamide | cid_44602375
Type:
Small organic molecule
Emp. Form.:
C15H11FN2O2S
Mol. Mass.:
302.323
SMILES:
Fc1ccc(NC(=O)Cn2sc3ccccc3c2=O)cc1
Structure:
Search PDB for entries with ligand similarity: