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Target
Sentrin-specific protease 8
Ligand
BDBM66065
Substrate
n/a
IC50
12000±892 nM
Citation
 PubChem, PC Dose-response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 using a kinetic assay with Nedd8 Protein Substrate PubChem Bioassay (2012)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM66065
Synonyms:
5-fluoranyl-7-nitro-quinolin-8-ol | 5-fluoro-7-nitro-8-quinolinol | 5-fluoro-7-nitro-quinolin-8-ol | 5-fluoro-7-nitroquinolin-8-ol | MLS000736929 | SMR000528432 | cid_260644
Type:
Small organic molecule
Emp. Form.:
C9H5FN2O3
Mol. Mass.:
208.146
SMILES:
Oc1c(cc(F)c2cccnc12)[N+]([O-])=O
Structure:
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