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Target
Protein skinhead-1
Ligand
BDBM93876
Substrate
n/a
IC50
7010±n/a nM
Citation
 PubChem, PC Dose ResponseConfirmation of SKN-1 Inhibitor hits in a fluorescence ratio assay - Set 2 PubChem Bioassay (2012)[AID] 
Target
Name:
Protein skinhead-1
Synonyms:
SKN1_CAEEL | SKiNhead family member (skn-1) | skn-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
70701.17
Organism:
Caenorhabditis elegans
Description:
P34707
Residue:
623
Sequence:
MGGSSRRQRSTSATRRDDKRRRRQCFSSVADDEEETTSIYGVSSIFIWILATSSLILVISSPSSNTSIQSSSYDRITTKHLLDNISPTFKMYTDSNNRNFDEVNHQHQQEQDFNGQSKYDYPQFNRPMGLRWRDDQRMMEYFMSNGPVETVPVMPILTEHPPASPFGRGPSTERPTTSSRYEYSSPSLEDIDLIDVLWRSDIAGEKGTRQVAPADQYECDLQTLTEKSTVAPLTAEENARYEDLSKGFYNGFFESFNNNQYQQKHQQQQREQIKTPTLEHPTQKAELEDDLFDEDLAQLFEDVSREEGQLNQLFDNKQQHPVINNVSLSEGIVYNQANLTEMQEMRDSCNQVSISTIPTTSTAQPETLFNVTDSQTVEQWLPTEVVPNDVFPTSNYAYIGMQNDSLQAVVSNGQIDYDHSYQSTGQTPLSPLIIGSSGRQQQTQTSPGSVTVTATATQSLFDPYHSQRHSFSDCTTDSSSTCSRLSSESPRYTSESSTGTHESRFYGKLAPSSGSRYQRSSSPRSSQSSIKIARVVPLASGQRKRGRQSKDEQLASDNELPVSAFQISEMSLSELQQVLKNESLSEYQRQLIRKIRRRGKNKVAARTCRQRRTDRHDKMSHYI
  
Inhibitor
Name:
BDBM93876
Synonyms:
4-(4-fluorophenyl)-N-(2-pyridinyl)-2-thiazolamine | 4-(4-fluorophenyl)-N-pyridin-2-yl-1,3-thiazol-2-amine | MLS001206910 | SMR000524296 | [4-(4-Fluoro-phenyl)-thiazol-2-yl]-pyridin-2-yl-amine | [4-(4-fluorophenyl)thiazol-2-yl]-(2-pyridyl)amine | cid_1092430
Type:
Small organic molecule
Emp. Form.:
C14H10FN3S
Mol. Mass.:
271.313
SMILES:
Fc1ccc(cc1)-c1csc(Nc2ccccn2)n1
Structure:
Search PDB for entries with ligand similarity: