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Target
Protein skinhead-1
Ligand
BDBM93895
Substrate
n/a
IC50
6400±n/a nM
Citation
 PubChem, PC Dose ResponseConfirmation of SKN-1 Inhibitor hits in a fluorescence ratio assay - Set 2 PubChem Bioassay (2012)[AID] 
Target
Name:
Protein skinhead-1
Synonyms:
SKN1_CAEEL | SKiNhead family member (skn-1) | skn-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
70701.17
Organism:
Caenorhabditis elegans
Description:
P34707
Residue:
623
Sequence:
MGGSSRRQRSTSATRRDDKRRRRQCFSSVADDEEETTSIYGVSSIFIWILATSSLILVISSPSSNTSIQSSSYDRITTKHLLDNISPTFKMYTDSNNRNFDEVNHQHQQEQDFNGQSKYDYPQFNRPMGLRWRDDQRMMEYFMSNGPVETVPVMPILTEHPPASPFGRGPSTERPTTSSRYEYSSPSLEDIDLIDVLWRSDIAGEKGTRQVAPADQYECDLQTLTEKSTVAPLTAEENARYEDLSKGFYNGFFESFNNNQYQQKHQQQQREQIKTPTLEHPTQKAELEDDLFDEDLAQLFEDVSREEGQLNQLFDNKQQHPVINNVSLSEGIVYNQANLTEMQEMRDSCNQVSISTIPTTSTAQPETLFNVTDSQTVEQWLPTEVVPNDVFPTSNYAYIGMQNDSLQAVVSNGQIDYDHSYQSTGQTPLSPLIIGSSGRQQQTQTSPGSVTVTATATQSLFDPYHSQRHSFSDCTTDSSSTCSRLSSESPRYTSESSTGTHESRFYGKLAPSSGSRYQRSSSPRSSQSSIKIARVVPLASGQRKRGRQSKDEQLASDNELPVSAFQISEMSLSELQQVLKNESLSEYQRQLIRKIRRRGKNKVAARTCRQRRTDRHDKMSHYI
  
Inhibitor
Name:
BDBM93895
Synonyms:
2-[4-(2-chloro-4-fluoro-benzyl)oxyphenyl]-1,3,4-oxadiazole | 2-[4-[(2-chloranyl-4-fluoranyl-phenyl)methoxy]phenyl]-1,3,4-oxadiazole | 2-[4-[(2-chloro-4-fluorophenyl)methoxy]phenyl]-1,3,4-oxadiazole | MLS001177102 | SMR000590320 | cid_9318929
Type:
Small organic molecule
Emp. Form.:
C15H10ClFN2O2
Mol. Mass.:
304.704
SMILES:
Fc1ccc(COc2ccc(cc2)-c2nnco2)c(Cl)c1
Structure:
Search PDB for entries with ligand similarity: