Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM93902
Substrate
n/a
IC50
>64000±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM93902
Synonyms:
3-(4-benzyl-7-chloro-3-keto-quinoxalin-2-yl)-N-[2-(dimethylamino)-2-phenyl-ethyl]propionamide | 3-(4-benzyl-7-chloro-3-oxoquinoxalin-2-yl)-N-[2-(dimethylamino)-2-phenylethyl]propanamide | 3-[7-chloranyl-3-oxidanylidene-4-(phenylmethyl)quinoxalin-2-yl]-N-[2-(dimethylamino)-2-phenyl-ethyl]propanamide | 3-[7-chloro-3-oxo-4-(phenylmethyl)-2-quinoxalinyl]-N-[2-(dimethylamino)-2-phenylethyl]propanamide | MLS001079652 | SMR000710303 | cid_24978977
Type:
Small organic molecule
Emp. Form.:
C28H29ClN4O2
Mol. Mass.:
489.008
SMILES:
CN(C)C(CNC(=O)CCc1nc2cc(Cl)ccc2n(Cc2ccccc2)c1=O)c1ccccc1
Structure:
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