Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM37242
Substrate
n/a
IC50
33500±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM37242
Synonyms:
5-(4-ethylphenyl)-3-(4-pyridyl)-1,2,4-oxadiazole | 5-(4-ethylphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole | MLS000109137 | SMR000105083 | cid_867086
Type:
Small organic molecule
Emp. Form.:
C15H13N3O
Mol. Mass.:
251.2832
SMILES:
CCc1ccc(cc1)-c1nc(no1)-c1ccncc1
Structure:
Search PDB for entries with ligand similarity: