Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM93767
Substrate
n/a
IC50
>64000±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM93767
Synonyms:
3-ethoxy-2-propyl-N-[4-(trifluoromethoxy)benzyl]indazole-6-carboxamide | 3-ethoxy-2-propyl-N-[[4-(trifluoromethoxy)phenyl]methyl]-6-indazolecarboxamide | 3-ethoxy-2-propyl-N-[[4-(trifluoromethoxy)phenyl]methyl]indazole-6-carboxamide | 3-ethoxy-2-propyl-N-[[4-(trifluoromethyloxy)phenyl]methyl]indazole-6-carboxamide | MLS000515493 | SMR000156399 | cid_11958432
Type:
Small organic molecule
Emp. Form.:
C21H22F3N3O3
Mol. Mass.:
421.4129
SMILES:
CCCn1nc2cc(ccc2c1OCC)C(=O)NCc1ccc(OC(F)(F)F)cc1
Structure:
Search PDB for entries with ligand similarity: