Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM93705
Substrate
n/a
IC50
4880±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM93705
Synonyms:
4-[4-[2-(4-fluorobenzyl)tetrazol-5-yl]benzyl]morpholine | 4-[[4-[2-[(4-fluorophenyl)methyl]-1,2,3,4-tetrazol-5-yl]phenyl]methyl]morpholine | 4-[[4-[2-[(4-fluorophenyl)methyl]-5-tetrazolyl]phenyl]methyl]morpholine | 4-[[4-[2-[(4-fluorophenyl)methyl]tetrazol-5-yl]phenyl]methyl]morpholine | 4-{4-[2-(4-Fluoro-benzyl)-2H-tetrazol-5-yl]-benzyl}-morpholine | MLS000068019 | SMR000006661 | cid_653359
Type:
Small organic molecule
Emp. Form.:
C19H20FN5O
Mol. Mass.:
353.3934
SMILES:
Fc1ccc(Cn2nnc(n2)-c2ccc(CN3CCOCC3)cc2)cc1
Structure:
Search PDB for entries with ligand similarity: