Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM39495
Substrate
n/a
IC50
4250±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM39495
Synonyms:
MLS000062478 | N-[4-(4-morpholinylmethyl)phenyl]-1-benzofuran-2-carboxamide | N-[4-(4-morpholinylmethyl)phenyl]-2-benzofurancarboxamide | N-[4-(morpholin-4-ylmethyl)phenyl]-1-benzofuran-2-carboxamide | N-[4-(morpholinomethyl)phenyl]coumarilamide | SMR000073241 | cid_892458
Type:
Small organic molecule
Emp. Form.:
C20H20N2O3
Mol. Mass.:
336.3844
SMILES:
O=C(Nc1ccc(CN2CCOCC2)cc1)c1cc2ccccc2o1
Structure:
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