Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM49327
Substrate
n/a
IC50
44100±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM49327
Synonyms:
2-(2,4-dichlorophenyl)-5-(prop-2-enylthio)-1,3,4-oxadiazole | 2-(2,4-dichlorophenyl)-5-prop-2-enylsulfanyl-1,3,4-oxadiazole | 2-(allylthio)-5-(2,4-dichlorophenyl)-1,3,4-oxadiazole | MLS000106052 | SMR000103023 | cid_1731558
Type:
Small organic molecule
Emp. Form.:
C11H8Cl2N2OS
Mol. Mass.:
287.165
SMILES:
Clc1ccc(-c2nnc(SCC=C)o2)c(Cl)c1
Structure:
Search PDB for entries with ligand similarity: