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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM90408
Substrate
n/a
IC50
1790±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule antagonists of the CRF-binding protein and CRF-R2 receptor complex in 384 well format PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM90408
Synonyms:
MLS000672418 | N-(2-methoxy-5-nitro-phenyl)-2-(methylthio)benzamide | N-(2-methoxy-5-nitro-phenyl)-2-methylsulfanyl-benzamide | N-(2-methoxy-5-nitrophenyl)-2-(methylthio)benzamide | N-(2-methoxy-5-nitrophenyl)-2-methylsulfanylbenzamide | SMR000296035 | cid_2227244
Type:
Small organic molecule
Emp. Form.:
C15H14N2O4S
Mol. Mass.:
318.348
SMILES:
COc1ccc(cc1NC(=O)c1ccccc1SC)[N+]([O-])=O
Structure:
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