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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM39983
Substrate
n/a
IC50
1360±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule antagonists of the CRF-binding protein and CRF-R2 receptor complex in 384 well format PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM39983
Synonyms:
2-(2-bromophenyl)-5-[(1-phenyl-1,2,3,4-tetrazol-5-yl)sulfanylmethyl]-1,3,4-oxadiazole | 2-(2-bromophenyl)-5-[(1-phenyltetrazol-5-yl)sulfanylmethyl]-1,3,4-oxadiazole | 2-(2-bromophenyl)-5-[[(1-phenyl-5-tetrazolyl)thio]methyl]-1,3,4-oxadiazole | 2-(2-bromophenyl)-5-[[(1-phenyltetrazol-5-yl)thio]methyl]-1,3,4-oxadiazole | MLS000056699 | SMR000065078 | cid_2621181
Type:
Small organic molecule
Emp. Form.:
C16H11BrN6OS
Mol. Mass.:
415.267
SMILES:
Brc1ccccc1-c1nnc(CSc2nnnn2-c2ccccc2)o1
Structure:
Search PDB for entries with ligand similarity: