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Target
Perilipin-5
Ligand
BDBM94587
Substrate
n/a
IC50
1579±n/a nM
Citation
 PubChem, PC Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) PubChem Bioassay (2012)[AID] 
Target
Name:
Perilipin-5
Synonyms:
LSDP5 | OXPAT | PAT-1 | PLIN5 | PLIN5_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50774.20
Organism:
Homo sapiens (Human)
Description:
gi_116292172
Residue:
463
Sequence:
MSEEEAAQIPRSSVWEQDQQNVVQRVVALPLVRATCTAVCDVYSAAKDRHPLLGSACRLAENCVCGLTTRALDHAQPLLEHLQPQLATMNSLACRGLDKLEEKLPFLQQPSETVVTSAKDVVASSVTGVVDLARRGRRWSVELKRSVSHAVDVVLEKSEELVDHFLPMTEEELAALAAEAEGPEVGSVEDQRRQQGYFVRLGSLSARIRHLAYEHSVGKLRQSKHRAQDTLAQLQETLELIDHMQCGVTPTAPACPGKVHELWGEWGQRPPESRRRSQAELETLVLSRSLTQELQGTVEALESSVRGLPAGAQEKVAEVRRSVDALQTAFADARCFRDVPAAALAEGRGRVAHAHACVDELLELVVQAVPLPWLVGPFAPILVERPEPLPDLADLVDEVIGGPDPRWAHLDWPAQQRAWEAEHRDGSGNGDGDRMGVAGDICEQEPETPSCPVKHTLMPELDF
  
Inhibitor
Name:
BDBM94587
Synonyms:
1-[1-(1H-benzimidazol-2-yl)-3-phenyl-propyl]-3-(2-furyl)quinoxalin-2-one | 1-[1-(1H-benzimidazol-2-yl)-3-phenyl-propyl]-3-(furan-2-yl)quinoxalin-2-one | 1-[1-(1H-benzimidazol-2-yl)-3-phenylpropyl]-3-(2-furanyl)-2-quinoxalinone | 1-[1-(1H-benzimidazol-2-yl)-3-phenylpropyl]-3-(furan-2-yl)quinoxalin-2-one | MLS003675343 | SMR001921264 | cid_53383516
Type:
Small organic molecule
Emp. Form.:
C28H22N4O2
Mol. Mass.:
446.4999
SMILES:
O=c1c(nc2ccccc2n1C(CCc1ccccc1)c1nc2ccccc2[nH]1)-c1ccco1
Structure:
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