Reaction Details Report a problem with these data
Target
Perilipin-5
Ligand
BDBM83461
Substrate
n/a
IC50
1167±n/a nM
Citation
 PubChem, PC Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) PubChem Bioassay (2012)[AID] 
Target
Name:
Perilipin-5
Synonyms:
LSDP5 | OXPAT | PAT-1 | PLIN5 | PLIN5_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50774.20
Organism:
Homo sapiens (Human)
Description:
gi_116292172
Residue:
463
Sequence:
MSEEEAAQIPRSSVWEQDQQNVVQRVVALPLVRATCTAVCDVYSAAKDRHPLLGSACRLAENCVCGLTTRALDHAQPLLEHLQPQLATMNSLACRGLDKLEEKLPFLQQPSETVVTSAKDVVASSVTGVVDLARRGRRWSVELKRSVSHAVDVVLEKSEELVDHFLPMTEEELAALAAEAEGPEVGSVEDQRRQQGYFVRLGSLSARIRHLAYEHSVGKLRQSKHRAQDTLAQLQETLELIDHMQCGVTPTAPACPGKVHELWGEWGQRPPESRRRSQAELETLVLSRSLTQELQGTVEALESSVRGLPAGAQEKVAEVRRSVDALQTAFADARCFRDVPAAALAEGRGRVAHAHACVDELLELVVQAVPLPWLVGPFAPILVERPEPLPDLADLVDEVIGGPDPRWAHLDWPAQQRAWEAEHRDGSGNGDGDRMGVAGDICEQEPETPSCPVKHTLMPELDF
  
Inhibitor
Name:
BDBM83461
Synonyms:
(phenylmethyl) N,N-dimethyl-N'-(C-methylsulfanyl-N-phenyl-carbonimidoyl)carbamimidothioate;hydroiodide | 2-benzyl-1,1-dimethyl-3-[C-(methylthio)-N-phenyl-carbonimidoyl]isothiourea;hydroiodide | MLS002701781 | N,N-dimethyl-N'-[(methylthio)-phenyliminomethyl]carbamimidothioic acid (phenylmethyl) ester;hydroiodide | SMR001565375 | benzyl N,N-dimethyl-N'-(C-methylsulfanyl-N-phenylcarbonimidoyl)carbamimidothioate;hydroiodide | cid_360443
Type:
Small organic molecule
Emp. Form.:
C18H21N3S2
Mol. Mass.:
343.509
SMILES:
CS\C(N=C(SCc1ccccc1)N(C)C)=N/c1ccccc1
Structure:
Search PDB for entries with ligand similarity: