Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM94888
Substrate
n/a
IC50
3490±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, via a fluorescence intensity assay PubChem Bioassay (2012)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM94888
Synonyms:
(2-phenyl-4-quinolyl)-(2-piperidinoethyl)amine | 2-phenyl-N-(2-piperidin-1-ylethyl)quinolin-4-amine | 2-phenyl-N-[2-(1-piperidinyl)ethyl]-4-quinolinamine | MLS001182180 | SMR000567889 | cid_2728458
Type:
Small organic molecule
Emp. Form.:
C22H25N3
Mol. Mass.:
331.454
SMILES:
C(CN1CCCCC1)Nc1cc(nc2ccccc12)-c1ccccc1
Structure:
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