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Target
Mitochondrial peptide methionine sulfoxide reductase
Ligand
BDBM95358
Substrate
n/a
IC50
102427±n/a nM
Citation
 PubChem, PC Absorbance-based biochemical high throughput dose response assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA) PubChem Bioassay (2013)[AID] 
Target
Name:
Mitochondrial peptide methionine sulfoxide reductase
Synonyms:
MSRA | MSRA protein | MSRA_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25822.90
Organism:
Bos taurus
Description:
gi_73586699
Residue:
233
Sequence:
MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK
  
Inhibitor
Name:
BDBM95358
Synonyms:
1-Methyl-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid (2,4,5-trimethoxy-benzylidene)-hydrazide | 1-methyl-6-oxidanylidene-N-[(E)-(2,4,5-trimethoxyphenyl)methylideneamino]pyridine-3-carboxamide | 1-methyl-6-oxo-N-[(E)-(2,4,5-trimethoxyphenyl)methylideneamino]-3-pyridinecarboxamide | 1-methyl-6-oxo-N-[(E)-(2,4,5-trimethoxyphenyl)methylideneamino]pyridine-3-carboxamide | 6-keto-1-methyl-N-[(E)-(2,4,5-trimethoxybenzylidene)amino]nicotinamide | MLS000566877 | SMR000175526 | cid_6868941
Type:
Small organic molecule
Emp. Form.:
C17H19N3O5
Mol. Mass.:
345.3499
SMILES:
COc1cc(OC)c(\C=N\NC(=O)c2ccc(=O)n(C)c2)cc1OC
Structure:
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