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Target
Mitochondrial peptide methionine sulfoxide reductase
Ligand
BDBM66635
Substrate
n/a
IC50
9911±n/a nM
Citation
 PubChem, PC Absorbance-based biochemical high throughput dose response assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA) PubChem Bioassay (2013)[AID] 
Target
Name:
Mitochondrial peptide methionine sulfoxide reductase
Synonyms:
MSRA | MSRA protein | MSRA_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25822.90
Organism:
Bos taurus
Description:
gi_73586699
Residue:
233
Sequence:
MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK
  
Inhibitor
Name:
BDBM66635
Synonyms:
MLS000737122 | SMR000528383 | [4-[(2Z)-2-(4-amino-2-methylsulfanyl-6-oxopyrimidin-5-ylidene)hydrazinyl]phenyl]arsonic acid | [4-[(2Z)-2-(4-azanyl-2-methylsulfanyl-6-oxidanylidene-pyrimidin-5-ylidene)hydrazinyl]phenyl]arsonic acid | [4-[(2Z)-2-[4-amino-2-(methylthio)-6-oxo-5-pyrimidinylidene]hydrazinyl]phenyl]arsonic acid | [4-[(N'Z)-N'-[4-amino-6-keto-2-(methylthio)pyrimidin-5-ylidene]hydrazino]phenyl]arsonic acid | cid_5992379
Type:
Small organic molecule
Emp. Form.:
C11H12AsN5O4S
Mol. Mass.:
385.231
SMILES:
CSc1nc(N)c(N=Nc2ccc(cc2)[As](O)(O)=O)c(=O)[nH]1 |w:8.8|
Structure:
Search PDB for entries with ligand similarity: